Agrochemicals vs NCD/CKDu Evidence Updated 23.11.2021

Serial No. Evidence Download Link
1. Chronic interstitial nephritis in agricultural communities is a toxin-induced proximal tubular nephropathy
(Vervaet et al.,2020)
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2. Chronic interstitial nephritis in agricultural communities: a new perspective on etiology, diagnosis and mechanism

(Vervaet et al.,2021)

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3. Impact of changing agricultural practices on human health: chronic kidney disease of multi-factorial origin in Sri Lanka

(Wimalawansa and Wimalawansa, 2014)

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4. CKD of Unknown Etiology (CKDu) in Sri Lanka: A Multilevel Clinical Case Definition for Surveillance and Epidemiological Studies

(Wijewickrama et al.,2019)

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5. Chronic interstitial nephritis of agricultural communities: continuing with the term CKDu (chronic kidney disease of unknown cause) is detrimental

(Chula Herath,2020)

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6. The incidence, prevalence and trends of Chronic Kidney Disease and Chronic Kidney Disease of uncertain aetiology (CKDu) in the North Central Province of Sri Lanka: an analysis of 30,566 patients

(Ranasinghe et al.,2019)

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7. Chronic kidney disease of unknown etiology in Sri Lanka

(Rajapakse et al.,2016)

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8. Chronic interstitial nephritis in agricultural communities: a worldwide epidemic with social, occupational and environmental determinants

(Jayasumana et al.,2016)

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9. Escalating chronic kidney diseases of multi-factorial origin (CKD-mfo) in Sri Lanka: causes, solutions, and recommendations—update and responses

(Sunil J. Wimalawansa,2014)

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10. Prevalence of chronic kidney disease in Sri Lanka: A profile of affected districts reliant on groundwater

(Kafle et al.,2019)

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11. Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka

(Athuraliya et al.,2011)

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12. Pesticide exposures and chronic kidney disease of unknown etiology: an epidemiologic review

(Valcke et al.,2017)

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13. Role of Organochlorine Pesticides in Chronic Kidney Diseases of Unknown Etiology

(Ghosh et al.,2018)

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14. The Environmental Audit report on the Pesticides Importing, Usage and its’ effect on Environment

Report No: PER/B/2019/02

NATIONAL AUDIT OFFICE

ENVIRONMENTAL AUDIT DIVISION

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15. Special Audit Inspection on Irregularities Occurred in the Implementation of the National Fertilizer Subsidy Programme

National Audit Office

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16. Phosphate fertilizer is a main source of arsenic in areas affected with chronic kidney disease of unknown etiology in Sri Lanka

(Jayasumana et al.,2015)

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17. Associations between exposure to heavy metals and the risk of chronic kidney disease: a systematic review and meta-analysis

(Jalilia et al.,2021)

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18. Heavy Metal Contamination and Accumulation in Groundwater and Food Crops in Sri Lanka: A Review

(Priyashantha and Mahendranathan,2019)

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19. EXPOSURE TO ARSENIC: A MAJOR PUBLIC HEALTH CONCERN

 

Preventing Disease Through Healthy Environments

28 October 2019| Publication

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20. Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation

(Ali et al.,2019)

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21. Exposure of children to chemical hazards in food –

WHO Fact Sheet

NO. 4.4 · MAY 2007 · CODE: RPG4_Food_Ex1

World Health Organization · Regional Office for Europe

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22. Arsenic and Cadmium Contamination in Water, Sediments and Fish is a Consequence of Paddy Cultivation: Evidence of River Pollution in Sri Lanka

(Perera et al.,2016)

 

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23. Heavy Metal Toxicity and the Environment

(Tchounwou et al.,2012)

 

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24. Cadmium Toxicity

Agency for Toxic Substances and Disease Registry

Case Studies in Environmental Medicine (CSEM)

U.S. Department of Health and Human Services Agency for Toxic Substances and Disease Registry – 2008

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25. Scientific Facts on Arsenic

GreenFacts Digest.

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26. Arsenic in Drinking-water

Background document for development of

WHO Guidelines for Drinking-water Quality

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27. Arsenic, Drinking-water and Health Risk Substitution in Arsenic Mitigation: a Discussion Paper

Guy Howard, 2003

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28. Fluoride in drinking water and diet: the causative factor of chronic kidney diseases in the North Central Province of Sri Lanka

(Ranjith W. Dharmaratne, 2015)

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29. Groundwater fluoride as a geochemical marker in the etiology of chronic kidney disease of unknown origin in Sri Lanka

(Dissanayake and Chandrajith,2017)

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30. Serum and urine fluoride levels in populations of high environmental fluoride exposure with endemic CKDu: a case–control study from Sri Lanka

(Fernando et al.,2020)

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31. Influence of fluoride on chronic kidney disease of uncertain aetiology (CKDu) in Sri Lanka

(Nanayakkara et al.,2020)

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32. Cancer

WHO Fact Sheet,2021

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33. List of classifications by cancer sites with sufficient or limited evidence in humans.

(IARC Monographs Volumes 1–129a)

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34. IARC MONOGRAPHS ON THE IDENTIFICATION OF CARCINOGENIC HAZARDS TO HUMANS

(IARC)

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35. Preventable Exposures Associated with Human Cancers

(Cogliano et al.,2010)

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36. Increased Cancer Burden Among Pesticide Applicators and Others Due to Pesticide Exposure

(Alavanja et al.,2013)

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37. Summary V1 on Agrochemicals and NCD CKDu Evidence Bank Download
38. Presentation: Agrochemicals and Health Download
39. Association of plasma and urine metals levels with kidney function: A population-based cross-sectional study in China

(Yang et al.,2019)

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40. The association between total urinary arsenic concentration and renal dysfunction in a community-based population from central Taiwan

(Chen et al.,2011)

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41. Associations between renal functions and exposure of arsenic and polycyclic aromatic hydrocarbon in adults living near a petrochemical complex

(Yuan et al.,2020)

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42. The association between plasma selenium and chronic kidney disease related to lead, cadmium and arsenic exposure in a Taiwanese population

(Wu et al.,2019)

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43. Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka

(Jayasumana et al.,2015)

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44. Chronic kidney disease of uncertain aetiology: prevalence and causative factors in a developing country

(Jayatilake et al.,2013)

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45. Agrochemicals and Chronic Kidney Disease of Multi-Factorial Origin (CKDmfo): An Environmentally Induced, Occupational Exposure Disease

(Sunil J Wimalawansa,2015)

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46. Chronic Kidney Disease of Unknown Etiology Should Be Renamed Chronic Agrochemical Nephropathy

(Saroj Jayasinghe,2014)

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47. Importance of Arsenic and pesticides in epidemic chronic kidney disease in Sri Lanka

(Jayasumana et al.,2014)

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48. Glyphosate exposures and kidney injury biomarkers in infants and young children

(Trasande et al.,2019)

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49. Organochlorine pesticide level in patients with chronic kidney disease of unknown etiology and its association with renal function

(Ghosh et al.,2017)

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50. Pesticides and childhood cancer: An update

(Michael Nasterlack,2007)

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51. Summary V2 on Agrochemicals and NCD CKDu Evidence Bank Download